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Introduction To Nitric Oxide

The nitric oxide molecule in the human body was first discovered in the 1980s. The discovery garnered a Nobel Prize in Physiology or Medicine to three U.S. scientists and launched a wave of research that continues to this day.

One of the body’s most important signaling molecules, nitric oxide (N-O) affects every organ, system, and function in the body. It truly is a master regulator of the cardiovascular system. N-O tells blood vessels and arteries to relax (i.e. dilate), promoting the healthy circulation that is essential for supporting total-body health.

  • Relaxing and widening your blood vessels for improved circulation, sexual health and blood pressure…
  • Strengthening – and even rebuilding – your bones…
  • Boosting memory and concentration…
  • And supporting the healthy function of virtually every organ in your body!

The problem is… your production of NO starts to decrease when you hit 40 – and only goes downhill from there the older you get. Testing to determine healthy levels of NO is therefore a critical wellness marker to evaluate. The easiest way to test for NO is to use Nitric Oxide Indicator Strips™.


The body’s ability – or inability – to manufacture N-O can be influenced by factors such as genetics, level of physical activity, toxin exposure, and diet.

Let’s look specifically at diet and some recent findings from human and animal studies. According to research, excessive sugar consumption is linked to cardiovascular and metabolic health problems. Healthcare providers aren’t surprised by these conclusions, but they are surprised by the way in which sugar creates cardio-metabolism havoc. Research is showing that excessive sugar creates lipid and glycemic changes that lead to N-O deficiency.

How exactly does this show up in the body? A 2014 analysis of controlled and random trials of eight weeks or longer revealed that higher sugar intake significantly increased blood pressure. Another recent study published in the online journal Open Heart reported that added sugars in processed foods likely play a greater role than salt does in disorders affecting the cardiovascular system.

For years, dietary guidelines have identified salt as a primary offender. Now researchers are focusing on sugar’s destructive effects on the cardiovascular system. They’ve found that consuming even small amounts of sugar in processed foods and beverages – think white breads and pastas; confectionaries, like cookies, cakes, and sweet breads; and sweetened beverages – slow down production of N-O and set off a chain reaction of related effects, such as increased inflammation in the body and damage to cells and membranes.


High sugar intake drains N-O by increasing glycation, a process that accelerates aging by damaging cells and creating a jumble of snarled tissue. The result? Wrinkled skin and inflexible, tough connective tissue throughout the body, including the internal organs.

Glycated tissues also generate aged glycation end-products, or AGEs, that create vast numbers of destructive free radicals and can increase inflammation. This process also may result in blocked N-O production. Loss of N-O caused by high sugar intake also creates critical blood glucose issues and related vascular problems. The result is a perpetual cycle of cause-and-effect issues.